Prognostic factors in renal-cell carcinoma: Immunohistochemical detection of p53 protein versus clinico-pathological parameters
نویسندگان
چکیده
منابع مشابه
Prognostic value of p53 in renal cell carcinoma
Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...
متن کاملprognostic value of p53 in renal cell carcinoma
background and objectives: rcc is one of the most common genitourinary cancers. accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. p53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle arrests after dna damage and apoptosis. presence of mutated p53 protein in tumors has been rel...
متن کاملClinico-pathological prognostic factors of renal cell carcinoma: A 15-year review from a single center in Greece
AIM To investigate the prognostic significance of certain clinical and pathological factors of renal cell cancer. MATERIALS AND METHODS One hundred and fourteen patients who underwent radical nephrectomy between 1996 and 2011 in our hospital were examined. Parameters including age, gender, mode of presentation, hematological and pathological parameters were evaluated for their role as predict...
متن کاملImmunohistochemical detection of p53 protein as a prognostic indicator in prostate carcinoma.
UNLABELLED THE AIM of our study was to evaluate the prognostic significance of p53 protein immunoreactivity for prostate cancer and to determine whether p53 immunoreactivity correlates with the Gleason tumor grade in primary adenocarcinoma. Prostate fragments were fixed in 10% formalin, paraffin-embedded, sectioned and standard Hematoxylin-Eosin stained, then examined using histological grade (...
متن کاملPrognostic factors in renal cell carcinoma
We studied 569 cases of renal cell carcinoma in the file5 of the Department of Pathology of the Nor~vegian Radium Hospital from 1964 to 1974. A nephrectorny had been perfornied in all cases. Clinical information on sex, age, survival time and metastases was traced. The histological slides were examined and turnour growth pattern, cell type, cell shape, nuclear atypia, abnormal nucleoli, nuclear...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1994
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.2910570504